BOTANY AND APPLIED PHARMACOGNOSY GROUP
BIOTECHNOLOGY AREA
Group coordinator
Dr. Lourdes Rufo Nieto | l.rufo.prof@ufv.es
Researchers
- José Manuel Bueno Calderón
- Beatriz González Gálvez
- María Luisa León Díaz
External collaborating researchers
- Vicenta de la Fuente García
- Irene Sánchez Gavilán (Student)
- Esteban Ramirez Chueca (Student)
Research Summary
Plants are plastic living beings that present a large number of adaptations to the environment due to their inability to move. Ecological environments considered extreme (salt marshes, mines, metalliferous soils, thermal deposits) present a special flora and vegetation where the degree of adaptation to certain environmental variables acquires its maximum expression.
The study of plant species growing in these environments has allowed us to identify and describe some of these strategies (hyperaccumulation of metals, formation of biominerals in the tissues, biosynthesis and accumulation of organic compounds with different functions, etc.). The products of these strategies can be of pharmacological utility (use of plant extracts and organic compounds with bioactive properties) and biotechnological utility (use of plant species or parts thereof in phytoremediation processes, as a basis for the manufacture, design or synthesis of new materials, etc.)
The studies carried out on the vegetation of the salt marshes of the Iberian Peninsula demonstrate the specificity of this flora and its ecological interest and pharmacological-biotechnological potential. It has been observed that, at least in the crass halophytes, the inorganic composition varies in relation to climatic variables. In addition, the existence of internal bio-mineralization processes has been demonstrated, as a result of which different salts crystallize and become visible throughout the year.
In addition, several halophytes studied contain high concentrations of phenols in their extracts. These extracts show antioxidant and cytoprotective activities. We are currently continuing to test for potential activity against malaria, COVID-19 and multidrug-resistant bacteria.

Projects in the last 5 years
- Study of halophytes from the interior of the Iberian Peninsula: characterization of biominerals, evaluation of biological activities and identification of compounds in their extracts. Period: 1/01/2020-31/12/2021. Funding: Universidad Francisco de Vitoria Research Grants
- Characterization of the halophytes of the inland salt marshes of the Iberian Peninsula and evaluation of the antioxidant capacity of their extracts. Period: 1/01/2018-31/12/2019. Funding: Universidad Francisco de Vitoria Research Grants.
- Characterization of the ecophysiological responses of the halophilic species Sarcocornia carinata and assessment of the antioxidant activity of its extracts. Period: 1/01/2016-31/12/2017. Funding: Universidad Francisco de Vitoria Research Grants.
Publications
- Rufo L, Iglesias MT, Fuente V. 2021. The endemic halophyte Sarcocornia carinata Fuente, Rufo & Sánchez-Mata (Chenopodiaceae) in relation to environmental variables: elemental composition and biominerals. Plant and Soil 460 : 189-209
- Ramírez E, Rufo L, Sánchez-Mata D, Sánchez-Gavilán I, Fuente V. 2021. Arthrocnemum macrostachyum plant communities in the Iberian Peninsula, Balearic and Canary Islands (Spain and Portugal). In: Pedrotti F., Box E.O. (eds) Tools for Landscape-Scale Geobotany and Conservation. Geobotany Studies (Basics, Methods and Case Studies). Springer, Cham. https://doi.org/10.1007/978-3-030-74950-7_12
- Sánchez-Gavilán I, Rufo L, Rodríguez N, Fuente V. 2021. On the elemental composition of the Mediterranean euhalophyte Salicornia patula Duval-Jouve (Chenopodiaceae) from saline habitats in Spain (Huelva, Toledo and Zamora). Environmental Science and Pollution Research 28: 2719-2727
- Rufo L, Iglesias MT, Rodríguez N, Ramírez E, Sánchez-Gavilán I, Fuente V. 2019. Mineralogy and seasonal variation of elemental composition of the endemic halophyte Sarcocornia carinata (Chenopodiaceae) in relation with the environmental variables. Written communication. 28th Meeting of the European Vegetation Survey. 2-6 September 2019
- Ramírez E, Rufo L, Sánchez-Mata D, Fuente V. 2019. Arthrocnemum meridionalis (Chenopodiaceae), a new species of Mediterranean flora. Mediterranean botany. http://dx.doi.org/10.5209/MBOT.59820. Press
- Fuente V, Rufo L, Sánchez-Gavilán I, Ramírez E, Rodríguez N and Amils R. 2018. Plant tissues and embryos biominerals in Sarcocornia pruinosa, a halophyte from the Río Tinto salt marshes. Minerals, 8, 505: 1-14 doi:10.3390/min8110505
- Rufo L., de la Fuente V., Sánchez-Mata D. 2016. Sarcocornia plant communities of the Iberian Peninsula and the Balearic Islands Phytocoenologia 46 (4): 383 – 396
- Fuente V; Rufo L; Rodríguez N; Sánchez-Mata D; Franco A; Amils R. 2016. A study of Sarcocornia A.J. Scott (Chenopodiaceae) from Western Mediterranean Europe. Plant Biosystems, 150 (2): 343-356